Rodent Poisons Losing Effectiveness: A Rising Concern
Experts warn that common rodent poisons are becoming less effective as new research indicates that mice and rats are evolving resistance to these substances.
Data shows a significant proportion of house mice are carrying genetic mutations linked to rodenticide resistance, enabling them to survive poisons that are typically used for pest control. Approximately 70% of urban house mice in the northeastern United States exhibit these mutations, along with about 35% of Norway rats, commonly known as brown or sewer rats.
Research conducted by Rutgers University investigated troubling reports from pest control experts facing increasingly stubborn rodent populations.
“Despite the use of effective rodenticides, rodent control is becoming more difficult in several areas,” stated Jin Jia Yu, lead author of the study.
The study analyzed DNA from 147 Mus musculus (house mice) and 143 Norway rats from northeastern states, including New York and Washington, DC.
Results revealed that a significant number of these rodents carry mutations in the Vkorc1 gene, which is known to confer resistance to anticoagulant rodenticides—the most widely used poisons in the US.
“We found that mouse resistance is more widespread than previously thought,” said Professor Yu. “While Norwegian rats also exhibited genetic mutations, researchers remain uncertain about the effects of these mutations on their sensitivity to rodenticides.”
According to study co-author Changlu Wang, rodents pose more than just a nuisance; they are a significant public health concern.
“As resistant rodent populations rise, it’s crucial to adopt science-based management strategies that safeguard both public health and the environment,” Wang emphasized.
“This research aids in understanding the evolving dynamics of rodent populations and underscores the need for adaptable management strategies.”
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Source: www.sciencefocus.com


